Computerworld has a very good article on RFID and it's impact on Business Operations and IT Infrastructure. The article identifies the opportunities enabled by RFID beyond the supply chain to fall into three categories: safety and security, mobile asset management and complex process simplification. The article then talks about the Impact of RFID on IT Strategy.

To realize the benefits of RFID, IT will need to upgrade its infrastructure in a number of areas, and the interfaces with the business will have to be closer than ever before. There are three areas that will be need to be addressed: data management, network and end-user device management, and a new category for many IT organizations, sensor management. In addition, tying all these together and integrating them with legacy systems will require a new level of systems integration capabilities.